BGI will be at BioGenomics 2017

From February 21-23, you will be able to find us at The BioGenomics 2017 conference to be held in the Smithsonian’s National Museum of Natural History in Washington DC. BGI is a proud sponsor and co-organizer. Please come by to say hi and discuss your NGS project needs. We are looking forward to seeing you.

Join BGI at the Plant and Animal Genomics Conference XXV, San Diego,


At our PAG Educational Seminar

“Examples of new NGS-Enabled Plant Research and Opportunities for Global Gene Banking Partnerships”

Monday, January 16, 6:10 – 8:20PM, in the Sunset Meeting House




Prof. Joshua Udall

Re-sequenced genomes reveal the genetic diversity of polyploid cotton.

Joshua A. Udall, Daojun Yuan, Mengqiao Pan, Evan Long, Spencer Hunt, Samantha McCord, Logan Brase, Lori Hinze, Jonathan F. Wendel, Vasu Kuraparthy, Richard Percy

By deep-sequencing many accessions of cotton, we have revealed detailed genetic information and phylogeographic patterns demonstrating the diversity in the cotton genome. We have re-sequenced more than 600 accessions, including 431 accessions of G. hirsutum, 165 accessions of G. barbadense, and other species. We detected the variation among these accessions and identified genetic variation between cultivars and wild species, also between the different species. This wealth of sequence information will allows us to identify which specific gene or genome region have been selected during domestication of cotton. Understanding the location of these loci will allow us to further improve the cotton genome for agricultural improvement.


Prof. Sally Mackenzie

Integrating genome-wide methylome and gene expression data in plant genomes

Mon-Ray Shao, Vikas Shedge, Robersy Sanchez, Xiaodong Yang, Sally Mackenzie

Genome-wide methylome analysis in plants conducted by bisulfite sequencing produces a highly heterogenous dataset that is difficult to associate with gene expression changes. Part of the data heterogeneity is dynamic DNA methylation behavior that serves to stabilize DNA, but which confounds analysis of methylation signal deriving from experimental treatment. We have conducted genome-wide bisulfite sequencing together with RNAseq in Arabidopsis and tomato lines that have undergone epigenetic reprogramming by suppression of the gene MSH1. We have developed a strategy for data analysis that permits more robust discrimination of signal to noise in methylome data, and integrated these data with transcriptome analysis to identify genes that display altered gene expression in association with intragenic DNA methylation changes. These analyses were also invaluable in detection of methylation changes that were aberrant in pattern, revealing them to be the consequence of germplasm contamination. We will present the various methodologies we have employed for mining these large datasets.


Dr. Xin Liu,

Large scale genomic studies at China National GeneBank

After 5 years of construction, the China National GeneBank (CNGB) was opened in September 2016.

CNGB, the first of its kind in China, is operated by BGI and will provide an open platform for global scientific research. So far, CNGB has established a bio-repository with the capacity to store tens of millions of samples, a database with a storage capacity of 20Pb as well as a living biobank. CNGB also offers an in-house sequencing infrastructure with the capacity to generate 10 Tb of data per day.

With this infrastructure, we have initiated several large scale genomic studies, including an avian genome project that will be introduced here, along with other examples of large scale genome projects currently under way.

As the CNGB is rapidly ramping up, we are open for additional global collaborations in which our infrastructure can add value.


BGI and Precision Medicine in Mountain View

BGI will join world leaders and host a session at the upcoming Precision Medicine World Conference, this coming January in Mountain View, California. BGI executives will explore the possibilities of the information from a low-cost genome for patients and society.


BGI PMWC Wang Jian

Jian Wang
M.D., President and Co-Founder, BGI

Healthcare in the Era of the Digitized Life
Genetic testing at extremely low costs, combined with imaging and other technologies, is digitizing human life, enabling more comprehensive diagnosis of disease risks and status. A new paradigm of healthcare is emerging with unprecedented power to allow human beings to live healthier and longer lives.



Yiwu He
Ph.D., MBA, Senior Vice President, Global Head of R&D, BGI

Implications of $100 Whole Genome Sequencing
We explore the healthcare impact of a $100 genome. Whole Genome Sequencing at consumer pricing will give healthcare providers a wealth of information on genetic links, risk factors of diseases, drug targets and drug reactions. The availability of precision medicine will benefit patients and society while lowering cost.



BGI Rade Drmanac PMWC

Rade Drmanac
Ph.D., Chief Scientific Officer, Complete Genomics, Inc. (a BGI company)

Efficient WGS as Foundation for Precision Medicine
A complete, accurate and phased WGS is critical to precision medicine. We describe an efficient massively parallel sequencing method using PCR-free process on patterned DNA-nanoball arrays, generating >1Tb (10 genomes) per microscope slide. When combined with co-barcoded reads, this platform generates the phased $100-WGS with quality needed for precision medicine.

Read more:



BGI Will Be Exhibiting At ASHG.

We are looking forward to seeing you at ASHG!

BGI is planning several inspiring activities at the conference. BGI scientists are presenting progress on a variety of topics in Genomics, and we will have an Educational seminar where leaders in the field of genomics will share their progress. Last but not least, there will be a chance to win FREE sequencing services!


“Examples of How NGS Enables Biomarker Discovery and Clinical Diagnostic Development”

Friday, October 21st, 1:00-2:30pm, Room 1 East Building.
Lunch will be provided.

Talk Titles and Speakers:

Next Generation Sequencing for Biomarker Discovery and Companion Diagnostics Development
Hirdesh Uppal, PhD., Senior Director, Predictive Diagnostics and Biomarkers,
Medivation, Inc.

Integrated Genomic Analysis for Precision Cancer Care
Marilyn Li, MD., Vice Chief, Division of Genomic Diagnostics, Director of Cancer Genomics Diagnostics, Children’s Hospital of Philadelphia

5 Years of Clinical Exome Sequencing – the Nijmegen Experience
Helger Yntema, PhD. , Laboratory Specialist Clinical Genetics, Head Genome Diagnostics Nijmegen, Radboud University Medical Center, Nijmegen

Reserve your place now by emailing us. Please make sure to include your name, position and place of



Talk Titles and Speakers:

Discovery and challenges in low-pass whole genome sequencing of over 140,000 individuals from throughout China
Xin Jin PhD. – Deputy Director, BGI Research
Plenary presentation
Plenary Session #66, Ballroom ABC, West Building
Friday, October 21, 4:30 PM – 5:50 PM
Abstract Program Number 245

Comparison of genetic heterogeneity between tumor tissues and circulating cell-free DNA in hepatocellular carcinoma
Xin Zhao – Research Scientist, BGI Research
Poster presentation
Poster Session: Molecular and Cytogenetic Diagnostics
Exhibit Hall B, West Building
Wednesday, October 19, 2:00 PM – 4:00 PM
Abstract Program Number 754/W

Evolution of multiple cell clones over a 29 year period of a CLL patient
Shiping Liu, PhD. – Bioinformatics Scientist, BGI Research
Poster presentation
Poster Session: Cancer Genetics
Exhibit Hall B, West Building
Thursday, October 20, 2:00 PM – 4:00 PM
Abstract Program Number 2909/T

Multiple-gene research and its clinical evaluation in chinese high-risk breast cancer
Guibo Li – Research Scientist, BGI Research
Poster presentation
Poster Session: Cancer Genetics
Exhibit Hall B, West Building
Friday, October 21, 2:00 PM – 4:00 PM
Abstract Program Number 2769/F

Enter Our ‘Unlock the Code’ Competition and Win $5,000 of FREE NGS Services!

A unique chance at ASHG to help unlock the potential of your genomics research! Sign up at and get your unique code.


Unlock the Code




BGI Will Be Exhibiting At ESHG.

BGI will be exhibiting at the ESHG Conference taking place 21st-24th May in Barcelona, Spain. Come and say hello to us at booth 620 and learn more about our global genomics services. Or, sign up for our seminar taking place on Saturday 21st May in room 120|121, 12:15pm, and hear about recent advances in next generation sequencing technology with success stories in clinical and research applications from some of our clients.

For advance registration for our seminar, please send an email to with the title ‘ESHG Seminar Registration’ in the subject field.

Seating is limited and space is allocated on a first come first served basis. Boxed lunches will be served for all participants.

For more information regarding talk titles and speakers, please click on the link below.

BGI Seminar at ESHG


June 3rd-7th, ASCO, Chicago, USA

BGI will be exhibiting at the American Society of Clinical Oncology conference (ASCO) taking place in Chicago, June 3rd-7th.
Email us at to arrange a meeting with a representative or to learn more about our ongoing oncology research or cancel panels.

October 18th-22nd, ASHG, Vancouver, Canada

BGI will be exhibiting at the ASHG conference taking place in Vancouver, Canada, October 18th-22nd.
Stay tuned for more information or email us at

2016 9-13 January. San Diego. PAG XXIV

The International Plant & Animal Genome XXIV brings together over 3,000 leading genetic scientists and researchers in plant and animal research, with over 130 exhibits, 150 workshops, 1100 posters and over 1800 abstracts. BGI will be exhibiting at the conference. Follow us on Twitter at @BGI_Genomics for our latest product updates and conference news.

2016 8-12 March. Tampa. ACMG

The ACMG Annual Clinical Genetics Meeting provides genetics professionals with the opportunity to learn how genetics and genomics are being integrated into medical or clinical practice. BGI will be exhibiting, come and say hello!

2016 May 21-24. Barcelona. ESHG

The European Human Genetics Conference (now in its 49th year) is a forum for all workers in human and medical genetics to review advances and develop research collaborations. BGI will be exhibiting, come and say hello!