16S/Metagenome + Metabolome

Service Description

BGI offers multi-omics services to look across genomics, transcriptomics, epigenomics, proteomics and metabolomics, with the flexibility to customize solutions that meet your specific needs. All projects are supported by a bioinformatics infrastructure that is second to none.
 

16S/Metagenome + Metabolome Correlation Analysis

In recent years, research on gut related diseases has developed rapidly and it is now thought that nearly 90% of diseases may be related to gut microbiota health. 16S/Metagenome + metabolome correlation analysis enables researchers to establish an association model between host metabolism and gut microbiota and explore the causal relationships between microbes and disease1,2.

Project Workflow

References

[1] Liu R, Hong J. et al. Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention. Nat Med. 2017 Jul;23(7):859-868.
[2] Liu H, Chen X. et al. Alterations in the gut microbiome and metabolism with coronary artery disease severity. Microbiome. 2019 Apr 26;7(1):68.

How to order

Request a Quote

Send us a no obligation request for quote and our dedicated sales team will reply to you within 24 hours.

Create an Online myBGI Account

Create a myBGI account to view all our sample and shipping documentation and to manage your project moving forwards. It's quick, free and easy!

Mass Spectrometry Service Specification

16S/Metagenome sequencing platform: 16S/Metagenome services.
Metabolome platform: Untargeted/Targeted Metabolomics and Lipidomics services.

  • Quality Standard

    Quality Standard

    • Summary includes data analysis
    • Reports provided in PDF format, RAW files available upon request
  • Turn Around Time

    Turn Around Time

    • Typical 2 weeks from LC-MS/MS raw data acceptance to data report delivery

Sample Requirements

Sample selection for 16S/Metagenome and Metabolome should be as consistent as possible.

Integrative Analysis

Biological duplicates when 2 groups

Biological duplicates when ≥ 3 groups

Metagenome + metabolome

≥ 8

≥ 6

16S+ metabolome

≥ 8

≥ 4

Clinical samples

≥ 30

≥ 30

Data Analysis

Metagenome + Metabolome Correlation Analysis

  • Quantitative correlation analysis

  • Functional correlation analysis

  • Phenotypes correlation analysis

16S + Metabolome Correlation Analysis

  • Rank correlation analysis

  • Canonical correlation analysis

  • Correlation network analysis

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