Targeted Metabolomics

Service Description

BGI has extensive experience in the field of targeted metabolomics spanning accurate quantification of target metabolites, verification of hypothesis by untargeted metabolomics or other omics, and metabolic model study for specific metabolites1.

Targeted Metabolomics

BGI’s targeted metabolomics service involves the detection and analysis for specific metabolites. By quantifying the small molecules with reference to established standards, BGI’s targeted metabolomics service can accurately monitor the dynamic metabolic process, uncover relevant metabolic mechanisms and verify potential metabolic biomarkers.

By applying state-of-the-art LC-MS/MS systems and techniques, BGI offers validated workflows of targeted metabolomics (vitamins, amino acids, hormones and 700+ kinds of small molecules).

 

Project Workflow

References

[1] Liu R., et al., Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention. Nat Med, 2017. 23(7): p. 859-868.

How to order

Request a Quote

Send us a no obligation request for quote and our dedicated sales team will reply to you within 24 hours.

Create an Online myBGI Account

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Mass Spectrometry Service Specification

Targeted Metabolomics services are performed using LC-MS, GC-MS and ICP-MS.

  • Sample Preparation and Services

    Sample Preparation and Services

    • Custom-developed UPLC-MRM/MS methods combine Isotope internal standard technology
    • Using LC-MS (SCIEX QTRAP 4500/5500/6500 and Waters Xevo TQ-S), GC-MS (Thermo TSQ 9000) and ICP-MS (Agilent 7700) to increase the scope of detection
  • Quality Standard

    Quality Standard

    • Summary includes all methods and data analysis
    • Reports provided in Excel or PDF format; RAW files available upon request
  • Turn Around Time

    Turn Around Time

    • Typical 3-5 weeks after sample receipt for raw data delivery

Sample Requirements

Please contact your BGI account representative for details for your samples.

Data Analysis

  • Data analysis performed with metaX1 and BGI library

  • Data quality control

  • Standard curves

  • Quantification results

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