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BGI has generated over 2097 publications in top-tier journals, such as Nature and Science. The list below is a selection from the total publications. (All links lead to external websites.)
2017
Metagenomics
Microorganism
seeksv: an accurate tool for somatic structural variation and virus integration detection Link
2015
Plant & Animal Resequencing
Animal
Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequencing Link
2015
RNA-seq(Q)
Human
Comparison of six different pretreatment methods for blood RNA extraction Link
2009
Plant & Animal Resequencing
Animal
Complete Resequencing of 40 Genomes Reveals Domestication Events and Genes in Silkworm (Bombyx) Link
2012
RNA-seq(Q)
Human
Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome Link
2016
Metagenomics
Microorganism
First report of human salivirus/klassevirus in respiratory specimens of a child with fatal adenovirus infection Link
2015
RNA-seq(Q)
Human
Full-length single-cell RNA-seq applied to a viral human cancer: applications to HPV expression and splicing analysis in HeLa S3 cells Link
2010
Plant & Animal Resequencing
Plant
Genome-wide patterns of genetic variation among elite maize inbred lines Link
2012
Small RNA
Plant
Identification of Soybean MicroRNAs Involved in Soybean Cyst Nematode Infection by Deep Sequencing Link
2015
Metagenomics
Microorganism
Mutational bias of Turnip Yellow Mosaic Virus in the context of host anti-viral gene silencing Link
2012
Plant & Animal Resequencing
Plant
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes Link
2010
Plant & Animal Resequencing
Plant
Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection Link
2016
RNA-seq(Q)
Human
RNA-Seq Reveals the Angiogenesis Diversity between the Fetal and Adults Bone Mesenchyme Stem Cell Link
2010
Small RNA
Sequencing bias: comparison of different protocols of microRNA library construction Link
2016
Metagenomics
Microorganism
Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome Link
2010
Epigenomics
Animal
Single base-resolution methylome of the silkworm reveals a sparse epigenomic map Link
2016
RNA-seq(Q)
Human
Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis Link
2013
RNA-seq(Q)
Human
SOAPfuse: an algorithm for identifying fusion transcripts from paired-end RNA-Seq data Link
2017
RNA-seq(Q)
Human
Single-cell RNA-seq reveals lincRNA expression differences in Hela-S3 cells Link
2013
Epigenomics
Human
Sorafenib Inhibits Epithelial-Mesenchymal Transition through an Epigenetic-Based Mechanism in Human Lung Epithelial Cells Link
2017
Small RNA
Plant
Transcriptome-Wide Identification and Prediction of miRNAs and Their Targets in Paris polyphylla var. yunnanensis by High-Throughput Sequencing Analysis Link
2010
Epigenomics
Human
Whole genome DNA Methylation analysis based on high throughput sequencing technology Link
2013
Plant & Animal Resequencing
Animal
Whole-genome sequencing of giant pandas provides insights into demographic history and local adaptation Link
2013
De Novo Genome Sequencing
Plant
Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation Link
2012
De Novo Genome Sequencing
Animal
Analyses of pig genomes provide insight into porcine demography and evolution Link
2016
Metagenomics
Microorganism
Detection of Listeria monocytogenes in CSF from Three Patients with Meningoencephalitis by Next-Generation Sequencing Link
2013
De Novo Genome Sequencing
Plant
Draft genome of the wheat A-genome progenitor Triticum urartu Link
2013
De Novo Genome Sequencing
Plant
Draft genome sequence of chickpea (Cicer arietinum) provides a resource for trait improvement Link
2016
Metagenomics
Microorganism
Effect of a long-term high-protein diet on survival, obesity development, and gut microbiota in mice Link
2015
De Novo Genome Sequencing
Plant
Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1) provides insights into genome evolution Link
2013
De Novo Genome Sequencing
Animal
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome Link
2014
Metagenomics
Microorganism
Influenza H7N9 and H9N2 Viruses: Coexistence in Poultry Linked to Human H7N9 Infection and Genome Characteristics Link
2016
Metagenomics
Microorganism
Metagenome-wide association studies: fine-mining the microbiome Link
2013
De Novo Genome Sequencing
Animal
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse Link
2012
Metagenomics
Microorganism
Revised genome sequence of Burkholderia thailandensis MSMB43 with improved annotation Link
2012
De Novo Genome Sequencing
Animal
The oyster genome reveals stress adaptation and complexity of shell formation Link
2016
De Novo Genome Sequencing
Animal
The seahorse genome and the evolution of its specialized morphology Link
2012
De Novo Genome Sequencing
Plant
The tomato genome sequence provides insights into fleshy fruit evolution Link
2018
Exome
Human
C/EBP β enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation link
2014
Exome
Human
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
link
2014
Exome
Human
Human intracellular ISG15 prevents interferon-α/βover-amplification and auto-inflammation.
link
2016
Exome
Human
Whole-exome sequencing implicates DGKH as a risk gene for panic disorder in the Faroese population
link
2018
Metagenomics
BGISEQ-500
Animal
A gene catalogue of the Sprague-Dawley rat gut metagenome
2018
BGISEQ-500
Plant
A guide to sequence your favorite plant genomes
2018
Metagenomics
BGISEQ-500
Human
A novel affordable reagent for room temperature storage and transport of fecal samples for metagenomic analyses
2018
RNA-Seq
BGISEQ-500
Plant
A novel HD-ZIP IV/MIXTA complex promotes glandular trichome initiation and cuticle development in Artemisia annua
2017
WGS
BGISEQ-500
Human
A reference human genome dataset of the BGISEQ-500 sequencer
2018
Exome
BGISEQ-500
Human
A novel PTCH1 mutation underlies non‐syndromic cleft lip and/or palate in a Han Chinese family
2018
Exome
BGISEQ-500
Human
A novel mutation in PRPF31, causative of autosomal dominant retinitis pigmentosa, using the BGISEQ-500 sequencer
2018
RNA-Seq
BGISEQ-500
Human
An integrated biomanufacturing platform for the large-scale expansion and neuronal differentiation of human pluripotent stem cell-derived neural progenitor cells
2018
RNA-Seq
BGISEQ-500
Animal
A small set of differentially expressed genes was associated with two color morphs in natural populations of the pea aphid Acyrthosiphon pisum
2018
RNA-Seq
BGISEQ-500
Human
An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation
2018
RNA-Seq
BGISEQ-500
Human
Anti‑fbrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn’s Disease
2017
Metagenomics
BGISEQ-500
Human
Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing
2017
RNA-Seq
BGISEQ-500
Plant
AtACS8 plays a critical role in the early biosynthesis of ethylene elicited by copper ions in Arabidopsis
2018
RNA-Seq
BGISEQ-500
Human
Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival
2018
RNA-Seq
BGISEQ-500
Animal
Cambogin suppresses dextran sulphate sodium‐induced colitis by enhancing Treg cell stability and function
2017
RNA-Seq
BGISEQ-500
Animal
Characteristics of NK cells from leukemic microenvironment in MLL-AF9 induced acute myeloid leukemia
2018
Small RNA
BGISEQ-500
Microorganism
Comparative genome-wide analysis of extracellular small RNAs from the mucormycosis pathogen Rhizopus delemar
2016
RNA-Seq
BGISEQ-500
Animal
Comparative transcriptome analysis of chemosensory genes in two sister leaf beetles provides insights into chemosensory speciation.
2018
RNA-Seq
BGISEQ-500
Plant
Comparative transcriptome analysis reveals key genes potentially related to soluble sugar and organic acid accumulation in watermelon
2018
Plastome DNA
BGISEQ-500
Plant
Complete plastome sequence of Dracaena cambodiana (Asparagaceae): a species considered “Vulnerable” in Southeast Asia
2018
RNA-Seq
BGISEQ-500
Animal
Cranial Irradiation Induces Hypothalamic Injury and Late-Onset Metabolic Disturbances in Juvenile Female Rats
2016
Small RNA
BGISEQ-500
Human
cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs
2017
RNA-Seq
BGISEQ-500
Animal
Data Descriptor: RNA sequencing analysis of activated macrophages treated with the anti-HIV ABX464 in intestinal inflammation
2018
RNA-Seq
BGISEQ-500
Microorganism
Differential gene expression in Escherichia coli during aerosolization from liquid suspension
2017
RNA-Seq
BGISEQ-500
Animal
Differential gene expression in the intestine of sea cucumber (Apostichopus japonicus) under low and high salinity conditions
2018
Small RNA
BGISEQ-500
Plant
DDM1 represses noncoding RNA expression and RNA-directed DNA methylation in heterochromatin
2017
RNA-Seq
BGISEQ-500
Human
Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells
2017
RNA-Seq
BGISEQ-500
Plant
Draft genome sequence of the Tibetan medicinal herb, Rhodiola crenulata
2017
RNA-Seq
BGISEQ-500
Animal
Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila
2018
RNA-Seq
BGISEQ-500
Animal
Dual extra-retinal origins of microglia in the model of retinal microglia repopulation
2017
RNA-Seq
BGISEQ-500
Human
Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon‐independent manner
2017
RNA-Seq
BGISEQ-500
Animal
Effects of In Utero PFOS Exposure on Transcriptome, Lipidome and Function of Mouse Testis
2018
Metagenomics
BGISEQ-500
Human
Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial
2017
RNA-Seq
BGISEQ-500
Human
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype
2017
RNA-Seq
BGISEQ-500
Animal
Exploring gene expression changes in the amphioxus gill after poly(I:C) challenge using digital expression profiling
2018
RNA-Seq
BGISEQ-500
Plant
Expression of grape ACS1 in tomato decreases ethylene and alters the balance between auxin and ethylene during shoot and root formation
2018
RNA-Seq
BGISEQ-500
Human
FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway
2017
RNA-Seq
BGISEQ-500
Human
FH535 Inhibits Proliferation and Motility of Colon Cancer Cells by Targeting Wnt/β-catenin Signaling Pathway
2017
RNA-Seq
BGISEQ-500
Plant
Gene expression profiling of ramie roots during hydroponic induction and adaption to aquatic environment
2018
RNA-Seq
BGISEQ-500
Animal
Genetic screening and multipotency in rhesus monkey haploid neural progenitor cells
2017
RNA-Seq
BGISEQ-500
Animal
Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions
2018
RNA-Seq
BGISEQ-500
Animal
Global expression profiling and pathway analysis of mouse mammary tumor reveals strain and stage specific dysregulated pathways in breast cancer progression
2017
RNA-Seq
BGISEQ-500
Human
Heterogeneous effects of M-CSF isoforms on the progression of MLL-AF9 leukemia
2017
RNA-Seq
BGISEQ-500
Human
High expression of diffuse panbronchiolitis critical region 1 gene promotes cell proliferation, migration and invasion in pancreatic ductal adenocarcinoma
2018
RNA-Seq
BGISEQ-500
Plant
Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor
2018
RNA-Seq
BGISEQ-500
Microorganism
Identification and Characterization of als Genes Involved in D-Allose Metabolism in Lineage II Strain of Listeria monocytogenes
2018
Exome
BGISEQ-500
Human
Identification of a mutL‑homolog 1 mutation via whole‑exome sequencing in a Chinese family with Gardner syndrome
2017
RNA-Seq
BGISEQ-500
Microorganism
Identification of differentially expressed genes involved in spore germination of Penicillium expansum by comparative transcriptome and proteome approaches
2018
Metagenomics
BGISEQ-500
Human
Identification of pathogens in culture-negative infective endocarditis with metagenomic analysis
2018
RNA-Seq
BGISEQ-500
Microorganism
In Situ Lignin Bioconversion Promotes Complete Carbohydrate Conversion of Rice Straw by Cupriavidus basilensis B-8
2018
RNA-Seq
BGISEQ-500
Animal
KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration
2018
RNA-Seq
BGISEQ-500
Human
Leukemia cell-derived microvesicles induce T cell exhaustion via miRNA delivery
2017
RNA-Seq
BGISEQ-500
Human
Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity
2017
RNA-Seq & ChIP-Seq
BGISEQ-500
Animal
Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response
2017
RNA-Seq
BGISEQ-500
Animal
Orally Administrated Baker’s Yeast beta-Glucan Promotes Glucose and Lipid Homeostasis in the Livers of ob/ob Mice
2018
RNA-Seq
BGISEQ-500
Human
Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through
repression of phosphoglycerate dehydrogenase
2017
RNA-Seq
BGISEQ-500
Plant
Overexpression of OsHSP18.0-CI Enhances Resistance to Bacterial Leaf Streak in Rice
2017
RNA-Seq
BGISEQ-500
Human
Overexpression of placenta specific 8 is associated with malignant progression and poor prognosis of clear cell renal cell carcinoma
2018
RNA-Seq
BGISEQ-500
Plant
Overexpression of VaWRKY14 increases drought tolerance in Arabidopsis by modulating the expression of stress-related genes
2018
RNA-Seq
BGISEQ-500
Animal
PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis
2017
RNA-Seq
BGISEQ-500
Human
PBRM1 restricts the basal activity of innate immune system through repressing RIG-I-like receptor signaling and is a potential prognostic biomarker for colon cancer
2018
RNA-Seq
BGISEQ-500
Plant
Phytochrome A Negatively Regulates the Shade Avoidance Response by Increasing Auxin/Indole Acidic Acid Protein Stability
2018
RNA-Seq
BGISEQ-500
Animal
Preinduction with bone morphogenetic protein-2 enhances cardiomyogenic differentiation of c-kit+ mesenchymal stem cells and repair of infarcted myocardium
2017
RNA-Seq
BGISEQ-500
Human
Probing impaired neurogenesis in human brain organoids exposed to alcohol
2018
BGISEQ-500
Human
Quality Control of Next-generation Sequencing-based In vitro Diagnostic Test for Onco-relevant Mutations Using Multiplex Reference Materials in Plasma
2017
RNA-Seq
BGISEQ-500
Human
Recessive mutation in EXOSC3 associates with mitochondrial dysfunction and pontocerebellar hypoplasia
2018
Methodology-index
BGISEQ-500
Reliable Multiplex Sequencing with Rare Index Mis-Assignment on DNB-Based NGS Platform
2018
RNA-Seq
BGISEQ-500
Animal
Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion
2018
Transcriptome resequencing
BGISEQ-500
Microorganism
RNA-Seq analysis of global transcriptomic changes suggests a roles for the MAPK pathway and carbon metabolism in cell wall maintenance in a Saccharomyces cerevisiae FKS1 mutant
2018
RNA-Seq
BGISEQ-500
Human
Roles of the CSE1L-mediated nuclear import pathway in epigenetic silencing
2018
RNA-Seq
BGISEQ-500
Human
Selenite and methylseleninic acid epigenetically affects distinct gene sets in myeloid leukemia: A genome wide epigenetic analysis
2018
RNA-Seq
BGISEQ-500
Human
Silkworm Pupa Protein Hydrolysate Induces Mitochondria-Dependent Apoptosis and S Phase Cell Cycle Arrest in Human Gastric Cancer SGC-7901 Cells
2018
Methodology-long fragment
BGISEQ-500
Single tube bead-based DNA co-barcoding for cost effective and accurate sequencing, haplotyping, and assembly
2018
RNA-seq(Q)
BGISEQ-500
Human
Single-cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood
2018
RNA-Seq
BGISEQ-500
Human
Small molecules capable of activating DNA methylation–repressed genes targeted by the p38 mitogen-activated protein kinase pathway
2018
RNA-Seq
BGISEQ-500
Human
STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection
2018
RNA-Seq
BGISEQ-500
Human
TBX3 promotes proliferation of papillary thyroid carcinoma cells through facilitating PRC2-mediated p57KIP2 repression
2017
RNA-Seq
BGISEQ-500
Animal
Systemic response of the stony coral Pocillopora damicornis against acute cadmium stress
2018
Transcriptome de novo
BGISEQ-500
Plant
The biosynthetic origin of psychoactive kavalactones in kava
2018
RNA-Seq
BGISEQ-500
Microorganism
The Catabolite Repressor/Activator Cra Is a Bridge Connecting Carbon Metabolism and Host Colonization in the Plant Drought Resistance-Promoting Bacterium Pantoea alhagi LTYR-11Z
2017
Epigenomics
BGISEQ-500
Human
The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.
2018
RNA-Seq
BGISEQ-500
Plant
The GARP/MYB-related grape transcription factor AQUILO improves cold tolerance and promotes the accumulation of raffinose family oligosaccharides
2018
RNA-Seq
BGISEQ-500
Animal
The LIS1/NDE1 Complex Is Essential for FGF Signaling by Regulating FGF Receptor Intracellular Trafficking
2018
RNA-Seq
BGISEQ-500
Human
The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1
2018
RNA-Seq
BGISEQ-500
Animal
The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis
2018
RNA-Seq
BGISEQ-500
Animal
Transcriptome profiling of immune-responsive genes in the intestine of Cynoglossus semilaevis Günther challenged with Shewanella algae
2018
Transcriptome de novo
BGISEQ-500
Animal
Transcriptome profiling reveals differential gene expression of detoxification enzymes in Sitophilus zeamais responding to terpinen-4-ol fumigation
2018
Transcriptome resequencing
BGISEQ-500
Plant
Transcriptome resequencing analysis of the responses of Ty5-Mediated
resistance to TYLCV via in resistant vs.
susceptible tomato cultivars
2017
RNA-Seq
BGISEQ-500
Plant
Transcriptome sequencing and comparative analysis of differentially-expressed isoforms in the roots of Halogeton glomeratus under salt stress
2017
Small RNA
BGISEQ-500
Animal
Transcriptome-wide analysis of immune-responsive microRNAs against poly (I:C) challenge in Branchiostoma belcheri by deep sequencing and bioinformatics
2017
RNA-Seq
BGISEQ-500
Animal
Transcriptomic analysis reveals transgenerational effect of hypoxia on the neural control of testicular functions
2017
RNA-Seq
BGISEQ-500
Animal
Using Next-Generation Sequencing to Detect Differential Expression Genes in Bradysia odoriphaga after Exposure to Insecticides
2018
RNA-Seq
BGISEQ-500
Human
Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy
2017
WGS
BGISEQ-500
Animal
Comparative performance of the BGISEQ-500 versus Illumina HiSeq2500 sequencing platforms for palaeogenomic sequencing
2018
RNA-seq & miRNA
BGISEQ-500
Human
Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy
2018
RNA-Seq
BGISEQ-500
Plant
Arabidopsis thaliana ACS8 plays a crucial role in the early biosynthesis of ethylene elicited by Cu2+ ions
2018
Transcriptome de novo
BGISEQ-500
Animal
Comparative transcriptome analysis of Sogatella furcifera (Horváth) exposed to different insecticides
2018
RNA-Seq
BGISEQ-500
Plant
Compositional and transcriptomic analysis associated with cuticle lipid production on rosette and inflorescence stem leaves in the extremophyte Thellungiella salsuginea
2017
RNA-Seq
BGISEQ-500
Microorganism
Coordination of metabolic pathways: Enhanced carbon conservation in 1,3-propanediol production by coupling with optically pure lactate biosynthesis
2017
RNA-Seq
BGISEQ-500
Plant
Genome-scale mRNA transcriptomic insights into the responses of oilseed rape (Brassica napus L.) to varying boron availabilities
2018
WGS
BGISEQ-500
Human
Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing
2018
Yeast DNA
BGISEQ-500
Microorganism
Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods