Whole Genome Sequencing

Whole Genome Sequencing

Whole Genome Sequencing Service Description

BGI’s human whole genome sequencing (WGS) detects the complete genome sequence at one time and provides the most comprehensive collection of an individual’s genetic variation based on the human reference genome. At BGI we’ve been providing whole human genome sequencing services for over 10 years to support researchers and companies all over the world with their genome sequencing needs, and have seen microarray-based genotyping studies gradually move to whole genome sequencing with the falling costs of sequencing technology.

Whole genome sequencing can be applied to human genetics and evolution studies to detect genome-wide genetic variations, pathogenic and susceptibility genes, and to enable genetic diversity and evolution analysis. It can also be applied to translational research to provide information on cancer and disease-associated mutations and is one of the most important approaches of precision medicine.


DNBSEQ™ NGS technology platform

BGI Human Whole Genome Sequencing services are typically executed with our proprietary DNBSEQ™ NGS technology platform, for great sequencing data at the lowest cost in the industry.

DNBSEQ™ is BGI’s proprietary sequencing technology, developed by our Complete Genomics subsidiary in Silicon Valley. This system is powered by combinatorial Probe-Anchor Synthesis (cPAS), linear isothermal Rolling-Circle Replication and DNA Nanoballs (DNB™) technology, followed by high-resolution digital imaging.

BGISEQ human whole genome sequencing

We are currently offering Human Whole Genome Sequencing from $600 including:

  • Sample QC, library construction and sequencing
  • High quality 90Gb 150/100PE data delivered in standard .fastq format
  • Multiple bioinformatics options available

Give our DNBSEQ™ based WGS services a try and find out why so many trust their valuable research samples to the world-class sequencing experience of BGI.

Request a No Obligation Quote!



Project Workflow

We care for your samples from the start through to the result reporting. Highly experienced laboratory professionals follow strict quality procedures to ensure the integrity of your results.

  • Sample QC
  • Library QC
  • Data QC
  • Delivery QC
  • Sample Preparation
  • WGS Library Preparation
  • Sequencing
  • Raw Data Output
  • Bioinformatics Analysis

How to order

Request a Quote

Send us a no obligation request for quote and our dedicated sales team will reply to you within 24 hours.

Create an Online myBGI Account

Create a myBGI account to view all our sample and shipping documentation and to manage your project moving forwards. It's quick, free and easy!

Sequencing Service Specification

BGI Human Whole Genome Sequencing services are executed with the DNBSEQ™ NGS technology platform with the benefit of lower cost and turn-around-times compared to other platforms.

  • Sample Preparation and Services

    Sample Preparation and Services

    • 150/100bp paired end sequencing
    • Raw data, standard and customized data analysis
    • CAP/CLIA laboratory services available
    • Cloud-based data storage and delivery system
  • Sequencing Quality Standard

    Sequencing Quality Standard

    • Guaranteed ≥ 80% of bases with quality score of ≥Q30
    • Standard sequencing coverage ≥30X; ≥60X is recommended for cancer sample
  • Turn Around Time

    Turn Around Time

    • Typical 18 working days from sample QC acceptance to filtered raw data availability
    • Expedited services are available, contact your local BGI specialist for details

Sample Requirements

We can process your gDNA, Blood, Cell line, Fresh frozen tissue and FFPE samples and
single-cell applications, with the following general requirements:

DNA concentration

Minimum sample volume

Regular Samples

Intact genomic DNA ≥ 1μg, Concentration ≥ 12.5ng/ μl

15 μl

PCR-free Samples

Intact genomic DNA ≥ 2μg, Concentration ≥ 12.5ng/ μl

15 μl

Low Input Samples

Intact genomic DNA ≥ 200ng, Concentration ≥ 2.5 ng/ μl

15 μl

Data Analysis

In addition to raw data output, BGI offers a range of standard and customized bioinformatics pipelines for your whole genome sequencing project.

Standard Analysis

  • Filtering

  • Alignment

  • SNP calling and annotation

  • SNP validation and comparison

  • SNP functionality and conservation prediction

  • SNP statistics per functional element

  • InDel calling and annotation

  • InDel validation and comparison

  • InDel statistics per functional element

  • CNV calling and annotation

  • SV calling and annotation

Available advanced analysis

  • Cancer Somatic SNV and InDel analysis

  • De novo mutation analysis for family samples

Customized analysis

Further customization of Bioinformatics analysis to suit your unique project is available: Please contact your BGI technical representative

WGS Resources

We care for your samples from the start through to the result reporting. Highly experienced laboratory professionals follow strict quality procedures to ensure the integrity of your results.

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