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    ChIP-Sequencing

    ChIP-Sequencing (ChIP-Seq) is widely used to analyze protein interaction with DNA. We have extensive experience supporting partners across the world with their ChIP-Seq research needs. Tell us about your project, our experts are here to help.

    ChIP Sequencing Introduction

    ChIP-Sequencing is widely used to analyze protein interaction with DNA. It combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify binding sites of DNA-associated proteins, and can be used to precisely map global binding sites for any protein of interest. ChIP sequencing offers higher resolution and more precise and abundant information in comparison to array-based ChIP-chip approaches.

    In addition to clean data output, BGI offers a range of standard, advanced and customized bioinformatics pipelines for your ChIP-Seq analysis project. We have particular expertise in the correlation analysis of RNA-Seq differential expression genes and ChIP-Seq peak related genes. Contact us for a no obligation discussion with our project experts.

    ChIP-Seq Service Overview

    • Sample Requirements

      ChIP DNA Samples
      - Mass: ≥ 10ng, Concentration: ≥ 1 ng/µl
      - Volume: 15 μl

      Full sample guidance is provided within the BGI Customer Account Portal.

    • Sequencing Standards

      • 50bp single-end sequencing reads
      • Cloud-based data storage and delivery system
      • Advanced and customized bioinformatics analysis
      • Standard output 20 Million reads per sample
      • Clean filtered sequencing data delivered in standard FASTQ file format

    • Key Service Details

      • Typical 25 working days from sample QC acceptance to final data delivery
      • Expedited services are available, contact your local BGI specialist for details
      • Reports and output data files are delivered in industry standard file formats: BAM, .xls, .png and FASTQ data.

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    ChIP Sequencing Technology

    BGI's ChIP Sequencing services are typically executed with proprietary DNBSEQ™ sequencing technology platforms, for great sequencing data at some of the lowest costs in the industry. DNBSEQ™ is a proprietary sequencing technology, first developed by BGI's Complete Genomics subsidiary in Silicon Valley and offers advantages in terms of lower amplification error rates and much lower duplication rates. In addition, studies have shown the index hopping rate in DNBSEQ™ platforms to be much lower when compared to that of other platforms.

    Contact us with any general enquiries or questions for our sequencing experts, we are here to help.

    Access Further Sequencing Resources

    We care for your samples from the start through to the result reporting. Highly experienced laboratory professionals follow strict quality procedures to ensure the integrity of your results. Access more sequencing resources below or sign up for a BGI Customer Account for full access to our range of educational resources and sample guides.

    Register for a BGI Account

    Opening a BGI Customer Account enables you to request a quote and order services from us. It also provides access to our range of educational resources including educational webinars providing practical sequencing tips and our complete sample preparation guides.

    Don’t hesitate to contact us to request a quote or to talk more about your requirements and how we can support your needs.