COLOTECT™ CRC Screening

Introduction

Colorectal cancer is a common cancer worldwide, and early detection is essential for better treatment outcomes. COLOTECTTM CRC Screening analyzes stool samples for specific DNA markers that indicate colorectal cancer or precancerous polyps. It offers a convenient and patient-friendly option, allowing for early detection without the discomfort or preparation required by traditional screening methods.

What clinical challenges are targeted by COLOTECT™ CRC Screening

In clinical practice, many patients hesitate to undergo colonoscopy due to concerns about discomfort, complex preparation, or fear of the invasive procedure. This reluctance results in low screening compliance, hindering early detection of colorectal cancer (CRC), which is critical for improving survival rates.

Stool-based biomarker tests offer a non-invasive alternative for CRC screening. These tests detect DNA methylation changes commonly seen in cancerous and precancerous cells, present in stool samples. By identifying these biomarkers, stool-based tests provide valuable insights for early detection and can guide further diagnostic steps, addressing the challenge of low adherence to traditional screening methods.

Applicable Clinical Scenarios

  • Individuals over 45 years old.
  • Individuals with a family history of colorectal cancer, which increases risk due to genetic factors, particularly among first-degree relatives diagnosed with CRC.
  • Individuals with unhealthy lifestyle habits, such as high intake of red and processed meat, smoking, and heavy drinking.
  • Individuals who are overweight or obese.
  • Individuals diagnosed with type II diabetes, as confirmed by a healthcare provider or through a diabetes association.

Important features of COLOTECT™ CRC Screening

Product NameCOLOTECTTM CRC Screening
Detection MethodMethylation-Specific qPCR / Methylation-Specific qPCR + Fecal Immunochemical Test
Option 1COLOTECTTM CRC Screening 1.0 (DNA Methylation Detection for Human SDC2, ADHFE1 and PPP2R5C Genes)
Option 2COLOTECTTM CRC Screening 3.0 (Combined Detection Kit for Human ADHFE1/OPLAH Genes Methylation and Fecal Occult Blood)
Sample TypeStool Sample


Why choose COLOTECT™CRC Screening

  • Private and Convenient
    The sample collection process is private and convenient for customers.
  • Non-invasive and Painless
    The test uses stool samples without requiring bowel preparation, making it non-invasive and painless.
  • Comprehensive Detection Method
    The Multi-biomarker offers a comprehensive method for detecting colorectal cancer and pre-cancerous lesions.
  • Total Solution
    BGI Genomics provides a total solution with COLOTECT™ 1.0/3.0, covering the entire process from sample collection to laboratory processing.

The COLOTECT™ CRC Screening

  • Step 1

    Physician orders test

  • Step 2

    Sample collected

  • Step 3

    Sample shipped to us and analyzed

  • Step 4

    Results sent to physician

Delivery Location: Hong Kong for COLOTECT™ 1.0, Denmark for COLOTECT™ 3.0 Turnaround Time (TAT) *: 7 Working Days for COLOTECT™ 1.0, 8 Working Days for COLOTECT™ 3.0 Note*: TAT is calculated from sample acceptance to report release.

Localization solution of COLOTECT™ CRC Screening

Automated Nucleic Acid ExtractionMethylation DetectionBioinformatics Analysis
EquipmentsThroughputEquipmentsThroughput
NE-38496-384 samples/runSlan-96S92 samples/runHalos
Purifier HT96 samples/runBioer 960092 samples/run
Purifier 3232 samples/runQuant Studio 592 samples/run
  • User-friendly control

User-friendly with high automation, enabling quick and efficient handling of large sample volumes.

  • Accurate detection

Automated DNA extraction and detection process, combined with advanced bioinformatics for accurate and comprehensive results

  • Flexible throughput

Metagenomic sequencing of 32-384 samples can be performed at a time depending on different platforms

  • Convenient and fast

For localized operation, TAT time from sample processing to obtaining report is within 24 hours

COLOTECT™ CRC Screening Resources

Learn more about our product solution by downloading our relevant materials.


【flyer】COLOTECT 1.0.pdf

【flyer】COLOTECT 3.0.pdf


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