Publications

BGI has generated over 2097 publications in top-tier journals, such as Nature and Science. *All links lead to external websites.

2015

RNA-seq(Q)

Human

Comparison of six different pretreatment methods for blood RNA extraction Link

2012

RNA-seq(Q)

Human

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome Link

2015

RNA-seq(Q)

Human

Full-length single-cell RNA-seq applied to a viral human cancer: applications to HPV expression and splicing analysis in HeLa S3 cells Link

2008

Epigenomics

Human

MethyCancer: the database of human DNA methylation and cancer Link

2016

RNA-seq(Q)

Human

RNA-Seq Reveals the Angiogenesis Diversity between the Fetal and Adults Bone Mesenchyme Stem Cell Link

2016

RNA-seq(Q)

Human

Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis Link

2013

RNA-seq(Q)

Human

SOAPfuse: an algorithm for identifying fusion transcripts from paired-end RNA-Seq data Link

2017

RNA-seq(Q)

Human

Single-cell RNA-seq reveals lincRNA expression differences in Hela-S3 cells Link

2013

Epigenomics

Human

Sorafenib Inhibits Epithelial-Mesenchymal Transition through an Epigenetic-Based Mechanism in Human Lung Epithelial Cells Link

2010

Epigenomics

Human

Whole genome DNA Methylation analysis based on high throughput sequencing technology Link

2018

Exome

Human

C/EBP β enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation link

2014

Exome

Human

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
link

2014

Exome

Human

Human intracellular ISG15 prevents interferon-α/βover-amplification and auto-inflammation.
link

2015

Exome

Human

The UK10K project identifies rare variants in health and disease
link

2014

Exome

Human

Identification of genomic alterations in oesophageal squamous cell cancer
link

2014

Exome

Human

Activating Hotspot L205R Mutation in PRKACA and Adrenal Cushing's Syndrome
link

2013

Exome

Human

A large-scale screen for coding variants predisposing to psoriasis
link

2016

Exome

Human

Genomic heterogeneity of multiple synchronous lung cancer
link

2016

Exome

Human

Whole-exome sequencing implicates DGKH as a risk gene for panic disorder in the Faroese population
link

2018

metagenome

DNBseq

Human

A novel affordable reagent for room temperature storage and transport of fecal samples for metagenomic analyses

2018

WES

DNBseq

Human

A novel mutation in PRPF31, causative of autosomal dominant retinitis pigmentosa, using the BGISEQ-500 sequencer

2018

WES

DNBseq

Human

A novel PTCH1 mutation underlies non‐syndromic cleft lip and/or palate in a Han Chinese family

2017

WGS

DNBseq

Human

A reference human genome dataset of the BGISEQ-500 sequencer

2018

RNA-Seq

DNBseq

Human

An integrated biomanufacturing platform for the large-scale expansion and neuronal differentiation of human pluripotent stem cell-derived neural progenitor cells

2018

RNA-Seq

DNBseq

Human

An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation

2018

RNA-Seq

DNBseq

Human

Anti‑fbrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn’s Disease

2017

Metagenomics

DNBseq

Human

Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing

2018

RNA-Seq

DNBseq

Human

Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival

2018

RNA-seq & miRNA

DNBseq

Human

Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy

2016

Small RNA

DNBseq

Human

cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs

2017

RNA-Seq

DNBseq

Human

Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

2017

RNA-Seq

DNBseq

Human

Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon‐independent manner

2018

metagenome

DNBseq

Human

Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial

2017

RNA-Seq

DNBseq

Human

Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype

2018

RNA-Seq

DNBseq

Human

FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway

2017

RNA-Seq

DNBseq

Human

FH535 Inhibits Proliferation and Motility of Colon Cancer Cells by Targeting Wnt/β-catenin Signaling Pathway

2018

WGS

DNBseq

Human

Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing

2017

RNA-Seq

DNBseq

Human

Heterogeneous effects of M-CSF isoforms on the progression of MLL-AF9 leukemia

2018

RNA-Seq

DNBseq

Human

High expression of diffuse panbronchiolitis critical region 1 gene promotes cell proliferation, migration and invasion in pancreatic ductal adenocarcinoma

2018

WES

DNBseq

Human

Identification of a mutL‑homolog 1 mutation via whole‑exome sequencing in a Chinese family with Gardner syndrome

2018

metagenome

DNBseq

Human

Identification of pathogens in culture-negative infective endocarditis with metagenomic analysis

2018

RNA-Seq

DNBseq

Human

Leukemia cell-derived microvesicles induce T cell exhaustion via miRNA delivery

2017

RNA-Seq

DNBseq

Human

Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity

2018

RNA-Seq

DNBseq

Human

Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase

2017

RNA-Seq

DNBseq

Human

Overexpression of placenta specific 8 is associated with malignant progression and poor prognosis of clear cell renal cell carcinoma

2017

RNA-Seq

DNBseq

Human

PBRM1 restricts the basal activity of innate immune system through repressing RIG-I-like receptor signaling and is a potential prognostic biomarker for colon cancer

2017

RNA-Seq

DNBseq

Human

Probing impaired neurogenesis in human brain organoids exposed to alcohol

2018

DNBseq

Human

Quality Control of Next-generation Sequencing-based In vitro Diagnostic Test for Onco-relevant Mutations Using Multiplex Reference Materials in Plasma

2017

RNA-Seq

DNBseq

Human

Recessive mutation in EXOSC3 associates with mitochondrial dysfunction and pontocerebellar hypoplasia

2018

RNA-Seq

DNBseq

Human

Roles of the CSE1L-mediated nuclear import pathway in epigenetic silencing

2018

RNA-Seq

DNBseq

Human

Selenite and methylseleninic acid epigenetically affects distinct gene sets in myeloid leukemia: A
genome wide epigenetic analysis

2018

RNA-Seq

DNBseq

Human

Silkworm Pupa Protein Hydrolysate Induces Mitochondria-Dependent Apoptosis and S Phase Cell Cycle Arrest in Human Gastric Cancer SGC-7901 Cells

2018

10X scRNA-seq

DNBseq

Human

Single-cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood

2018

RNA-Seq

DNBseq

Human

Small molecules capable of activating DNA methylation–repressed genes targeted by the p38 mitogen-activated protein kinase pathway

2018

RNA-Seq

DNBseq

Human

STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection

2018

RNA-Seq

DNBseq

Human

TBX3 promotes proliferation of papillary thyroid carcinoma cells through facilitating PRC2-mediated p57KIP2 repression

2017

ChIP-Seq

DNBseq

Human

The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer.

2018

RNA-Seq

DNBseq

Human

The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

2018

RNA-Seq

DNBseq

Human

Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy

2019

Single Cell RNA Sequencing

DNBseq

Animal

Sanger, Garvan Teams Find BGI Tech Comparable With Illumina for
Single-Cell RNA Sequencing Link

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