Proteomic Services

Proteomic Services

Service Description

Proteomics and metabolomics data are increasingly combined with genomics information in multi-omics studies to enhance basic research and drug development projects. BGI has pioneered the field of multi-omics and offers advanced proteomics and bioinformatics solutions to support our client’s research1,2.

Recent advances in Mass Spectrometry have provided powerful tools for the analysis of proteins from a variety of organisms and cell types. BGI applies state-of-art MS-based techniques for protein identification, protein characterization, relative and absolute quantitation, as well as for the study of post-translational modifications and protein-protein interactions.

Workflow

We care for your samples from the start through to the result reporting. Highly experienced laboratory professionals follow strict quality procedures to ensure the integrity of your results.

  • Sample QC
  • Data QC
  • Delivery QC
  • Sample Preparation
  • LC-MS/MS
  • Raw Data Output
  • Bioinformatics Analysis

Request for Information or Quotation

Contact your BGI account representative for the most affordable rates in the industry and to discuss how we can meet your specific project requirements or for expert advice on experiment design, from sample to bioinformatics.


References 

 

1) Xun Z, Shangbo X et al. Tissue-specific Proteogenomics Analysis of Plutella xylostella Larval Midgut Using a Multialgorithm Pipeline. Mol Cell Proteomics. 2016; 15(6): 1791-1807. doi: 10.1074/mcp.M115.050989
2) Zhen C, Bo W et al. Quantitative proteomics reveals the temperature-dependent proteins encoded by a series of cluster genes in thermoanaerobacter tengcongensis. Mol Cell Proteomics. 2013; 12(8): 2266-2277. doi: 10.1074/mcp.M112.025817
3) Wen B, Zhou R, et al. IQuant: an automated pipeline for quantitative proteomics based upon isobaric tags. Proteomics. 2014; 14(20):2280-5

Service Specification

BGI proteomics services are available from our state-of-the-art proteomics laboratory, where experienced personnel care for your samples. A variety of LC-MS/MS systems are available to fit the needs of your unique project.

  • Proteomic Services

    Proteomic Services

    • Protein characterization
    • Protein quantification – iTRAQ and Label-free
    • Phosphorylation Identification
  • Turn Around Time

    Turn Around Time

    • Typical 40 working days after sample receipt for raw data delivery
    • Expedited services are available, contact your local BGI specialist for details

Data Analysis

The output of a proteome analysis includes all raw MS data, protein hit identification, gene ontology and pathway analysis, expression pattern cluster analysis, etc.

BGI employs a wide range of data analysis tools that can satisfy different needs based on customers’ unique projects. BGI’s in-house developed software includes BGI IQuant for quantitative proteomics analysis and BGI IPeak for peptide identification.

3rd party software tools include:

  • Mascot

  • Maxquant

  • Proteinpilot

  • Peakview

  • Spectronaut

  • Progenesis QI

 

Sample Requirements

We can process a large variety of tissue and cell sample types, such as fresh animal and plant tissue, microorganism, cell, blood, plasma, serum, urine etc., as well as gel and protein samples.
Contact your BGI account representative for details for your samples.